SOCIAL ENRICHMENT DURING POSTNATAL DEVELOPMENT INDUCES TRANSGENERATIONAL EFFECTS ON EMOTIONAL AND REPRODUCTIVE BEHAVIOR IN MICE

Social enrichment during postnatal development induces transgenerational effects on emotional and reproductive behavior in mice

Across species there is evidence that the quality of the early social environment can have a profound impact on neurobiology and behavior.In the present study we explore the effect of communal rearing conditions (3 dams with 3 litters per cage) during the postnatal period on offspring (F1) and grand-offspring (F2) anxiety-like and maternal behavior

read more

Experimental artefacts can lead to misattribution of bioactivity from soluble mesenchymal stem cell paracrine factors to extracellular vesicles

It has been demonstrated that some commonly used Extracellular Vesicle (EV) isolation techniques can lead to substantial contamination with non-EV factors.Whilst it has been established that this impacts the identification of biomarkers, the impact on apparent EV bioactivity has not been explored.Extracellular vesicles have been implicated as criti

read more